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Administration of iAluRil® Prefill by catheter may only be carried out by qualified medical personnel under controlled sterility and monitoring. Not for self administration.
iAluRil Prefill Syringe, is used to treat Interstitial cystitis/painful bladder syndrome, recurring UTI’s chemical cystitis etc. It works directly on the bladder lining to form a protective barrier between the bladder lining & the irritant compounds found in urine.
In a healthy bladder there is a natural barrier that protects the bladder lining from irritating and toxic substances found in urine. This barrier is called the glycosaminoglycan (GAG) layer. Damage to this causes urine to come into direct contact with the tissues of the bladder lining.
If this happens for an extended period, it can cause damage to these tissues and allow bacteria to stick. This damage can lead to several other problems that cause symptoms, such as pain, urgency (the need to go to the toilet immediately), frequency (the need to go to the toilet more often) and recurrent urinary tract infections (UTIs).
By administering iAluRil directly into the bladder, the combination of ingredientsthat make up iAluRil, can help repair the damage to the GAG layer and restore the bladder’s protective coating; thereby, relieving these symptoms in some patients.
This medical device has a combination of water, calcium chloride, hyaluronic acid and chondroitin sulphate.
iAluRil is used when the loss of components of the bladder lining can cause:
- Interstitial cystitis/painful bladder syndrome
- Chemical cystitis – damage to the bladder lining caused by chemotherapy
- Radiotherapy-induced cystitis – damage to the bladder lining caused by radiation to the pelvis
- Recurrent urinary tract infections
- In cases where the loss of the GAG layer is associated with forms of chronic inflammation in which the composition and integrity appears compromised in different ways
Hyaluronic Acid (1.6% - 800mg/50ml), sodium chondroitin sulphate (2% - 1g/50ml) and Calcium chloride (0.87% - 44mg/50ml)
* GAG (glycosaminoglycan) layer: the barrier that protects the bladder lining from irritating and toxic substances found in urine.
This treatment is administered as a course of instillations generally over 2-6 months, depending on the condition you are being treated for.
Throughout the course of instillations, your doctor will assess your response to treatment.
1) Before administering iAluRil®, your bladder will need to be emptied. This can be done either by urinating or by inserting a thin catheter through the urethra into the bladder and waiting for the urine to drain.
2) Your doctor may perform an ultrasound to ensure that the bladder has been emptied sufficiently, after which this treatment is administered directly into the bladder.
3) Once the iAluRil has been instilled into your bladder it should be held there for at least half an hour to allow the contents to bond, however it can be held for as long as possible or practical.
4) Once it can be held no more, the bladder can be emptied by urinating as normal. This is a relatively simple, painless and routine procedure, which will most likely be carried out by a doctor or a nurse.
Store in a cool dry place.
Always read the label and follow the directions for use. Keep out of reach of children. Not to be used without the instructions of a healthcare professional. This medicine may not be right for you. If symptoms persist please consult your healthcare professional
http://www.ialuril.com.au/downloads/JUN_0042_iAluRil_MED16.2_ProductInfo.pdf
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